Reduce Breast Cancer with Fruits and Vegetables
Fruits and Vegetables Can Reduce Breast Cancer Risk
July, 2001
Importance of the study: Your parents’ claim that “fruits and veggies are good for you” has further support from new research. While past studies have found that diets high in fruits and vegetables may protect against many types of cancer, the evidence was not compelling for breast cancer. This study tried to determine if there was some link between carotenoid-containing fruits and vegetables and breast cancer risk. All of us want to know how to protect ourselves from cancer—particularly with practical dietary measures that we can take ourselves every day.
Words on this page
carotenoids
antioxidant
free radicals
gene
Background: Carotenoids are pigments that are present in most plants (they’re what make carrots orange, for instance, and actually protect some plants from sunburn!). They also have proven antioxidant properties, meaning they protect cells against the damaging effects of free radicals. Free radicals are unstable molecules that occur normally in your body. They start out with a positive charge, then neutralize it by “stealing” an electron (a negatively charged particle to balance out the positive charge) from healthy molecules nearby. The healthy cells can be damaged, particularly if the “stolen” electrons come from the bonds that hold their genetic material together. Significant damage to the genes can disrupt business as usual in the cells. If the genetic damage isn’t fixed, cells can grow out of control, leading to the start of a cancer. Foods that calm down the free radicals with their antioxidant powers may help spare normal tissue from this kind of damage.
Study design: In this study, New York University researchers measured the levels of carotenoids in the blood samples of 270 women who developed breast cancer up to 11 years after the samples were taken. They compared these levels with the carotenoid levels in the blood of 270 similar women who remained cancer-free. The investigators measured several carotenoids, including beta- and alpha-carotene (found in orange and leafy green vegetables and orange-colored fruits), lutein (found in leafy green vegetables such as spinach), and beta-cryptoxanthin (found in oranges). They then examined the possible connection between blood levels of carotenoids and the risk of developing breast cancer.
Study results: Lower blood levels of carotenoids were associated with a higher risk of breast cancer. Women with the lowest levels of carotenoids had double the breast cancer risk of women with the highest carotenoids levels.
Take-home message: Your parents were right on this one: Eat your fruits and vegetables! It makes sense that anyone would benefit from eating lots of fresh fruits and vegetables, but we can’t say for sure if carotenoids will lower the risk of recurrent or new breast cancers in women who have already had breast cancer. Some easy ways to make sure you get at least five fruits and vegetables in a day (nine is better):
Add chopped squash and carrots to jarred or fresh spaghetti sauce (serve on pasta for a great dinner).
Eat tomatoes, tomatoes, tomatoes—raw in salad, sandwiches, salsa, juice, alone (like fruit), cooked in sauces.
Drink a fruit puree shake every morning (throw in plain nonfat yogurt and call it breakfast).
Munch on cleaned, baby carrots (keep a cooler of them in the car).
Throw handfuls of spinach into stews and soups (imagine what you could accomplish, Popeye!).